RNA Details
Disease Name
kidney diseases
Tissue
kidney
RNA Symbol
mir-144
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
NA
Target
TPA;MMP9
Pathway
PI3K-AKT SIGNALING PATHWAY
PubMed ID
Title
Erythropoietin protects the tubular basement membrane by promoting the bone marrow to release extracellular vesicles containing tPA-targeting miR-144
Year
2016
Function
"Erythropoietin protects mus musculus renal through promoting bone marrow cells to generate and secrete miR-144, which, in turn, is efficiently delivered into the mus musculus kidney via extracellular vesicles (EVs) to inhibit the activation of the TPA/MMP9-mediated proteolytic network."